Make Your Selection Below

Freeze Dryers & Fill-Finish Processing Lines Technical Servicing & Maintenance Aseptic Processing Line & Fill-Finish Equipment Pilot/ R&D Freeze Dryers Laboratory Benchtop Freeze Dryers Production Freeze Dryers

Freeze Dryers & Fill-Finish Processing Lines Technical Servicing & Maintenance Aseptic Processing Line & Fill-Finish Equipment Pilot/ R&D Freeze Dryers Laboratory Benchtop Freeze Dryers Production Freeze Dryers

Freeze Dryers, Aseptic Processing Lines And Fill-Finish Equipment – Full Service Solutions For Ireland

Choose BPS Crowthorne – the only freeze dryer supplier to offer Irish customers a full range of lyo and aseptic processing line/fill-finish solutions for a complete end-to-end service:

  • Benchtop, pilot/R&D and production-scale freeze dryers configured and supplied to best meet to your project and application requirements
  • Full aseptic processing lines including external and rotary vial washers, depyrogenation tunnels, filling and stoppering machines, capping machines and trayloaders
  • Lyo-laboratory – independent R&D, pre-formulation studies, cycle review and development, formulation development, validation of lyo storage and transportation
  • Freeze drying training courses conducted by highly experienced freeze drying specialists.
  • Servicing and maintenance - expert freeze drying equipment engineers on the road, providing support in the form of regular servicing, general maintenance to extend the life of your equipment and to keep it running efficiently, or in the event of a break down.

BPS Crowthorne combines the expertise of Biopharma Group and Crowthorne Group into one easily accessible one-stop-shop solution:

  • delivering the lyophilisation solutions you need seamlessly
  • solving your challenges with freeze dryers, consultancy, training and support tailored to your specific requirements
  • ensuring your lab or cleanroom is maintained and validated for safe working and production environments.

Offering The Best Freeze Dryer Solution To Meet Your Requirements

Let’s discuss your requirements for a freeze dryer and the application or project that it’s for. We’ll match you to the best freeze dryer (and the optimum configuration of that model) that will best meet your needs.

Here are some key questions to consider when choosing a new freeze dryer:

  1. Regulatory requirements – does your project need to comply with any particular regulations e.g. 21 CFR Part 11 for example?
  2. Product – what do you need to process and freeze dry? Do you need to maintain flavour/appearance? Extend shelf life? Slow down biological activity? Prevent decay?
  3. Solvent – is your formulation aqueous-based only? Or will it also include any non-aqueous-based solvents? Most products have only one solvent (water) which has a relatively high freezing temperature (making it easy to freeze dry). Others, however, can include acetic acid, acetone, acetonitrile, cyclohexane, diethylene glycol, hydrochloric acid, hydrogen peroxide (28%), methyl alcohol (100%), nitric acid (concentrated) and propylene glycol. Some non-aqueous solvents can create corrosion issues – so your freeze dryer will need stainless steel and glass components. Acrylic components will need to be replaced.
  4. Is your product ready for freeze drying? Not all products or formulations can be easily freeze dried. They may need pre-processing or alternative stabilisation methods. Our laboratory team can advise you on this.
  5. What is the end use? What will happen to your product after it leaves the freeze dryer? Will it used for pharmaceutical or biotech purposes? Is it for ingestible use? Is it for incorporation into another product? Sent for further analysis? You may need a cleanroom environment – but not all freeze dryers can be used in cleanrooms.
  6. Throughput – how much material do you need to freeze dry in each batch? You will need to calculate the volumes based on the specific type of container required (vials, bulk trays, 96 well plates). You will also need to calculate for batch variables. Factor in the cycle duration and also the time involved for loading and unloading, defrosting, cleaning and maintenance.
  7. Container – what kind of container will you require? Vials, trays, Eppendorf tubes? Vials must be sealed in the chamber using a built-in stoppering mechanism. Pneumatic stoppering is available only on models with fully controllable shelves (such as the Advantage Pro). Important: this functionality must be specified in advanced – it cannot be retrofitted. You can change the container type to increase/decrease the amount of product that will fit on a shelf; but this will change the freeze drying cycle parameters – so you will need to assess the effect on the freeze drying cycle.
  8. Where will the freeze dryer be positioned? Will it sit on a bench? Or will it be a production freeze dryer in a plant room? Freeze dryers work more efficiently in a temperature-controlled environment. The ideal temperature is 20-22°C.


Laboratory/Benchtop Freeze Dryers

Benchtop Pro

Compact research machines for lab processing. Flexible, powerful, user-friendly:

  • condenser temperature options from -55°C to -103°C for processing a wide range of products and solvents
  • extensive range of accessories including trays, flasks, ampoules, vials and 96 well microtiter plates manifolds in clear acrylic (or stainless steel for superior corrosion resistance)
  • precise vacuum control gives you better results and greater consistency
  • one-button auto start-up/shut-down activates all operating parameters in a correct and safe sequence, protecting the product and the equipment
  • hot gas defrost and smooth-walled condensers for fast turnaround and minimal delay between runs.

You must freeze samples externally before introducing them to the vacuum. Need to freeze products in a benchtop machine? Either specify a Freezemobile Shell Bath Freezer to go with your Benchtop Pro – or specify the AdVantage series (which can freeze in situ)…

AdVantage Series Freeze Dryers

AdVantage freeze dryers are ideal for pilot or R&D laboratories that need advanced process control but lack the space for freestanding research units. They are commonly used by biotech and pharma corporations, research institutes, pharmacy departments of universities and diagnostic companies.

Specify an AdVantage benchtop freeze dryer for:

  • advanced software for data capture and analysis
  • up to 16 multi-step program recipes – control shelf temperature (-62°C to +60°C), condenser temperature and vacuum levels
  • thermocouple probes for product and process monitoring are included
  • complementary PC software for data capture and analysis is also available
  • up to 3x stainless steel 316L shelves (0.27m2 total shelf area), condenser temperatures as low as -82°C
  • pneumatic stoppering allows containers to be closed at the end of a product run, under either vacuum or an inert gas, such as nitrogen
  • precise freeze drying control – ideal for processing valuable or sensitive biological materials.

Freezemobile Shell Bath Freezer

These floor-based refrigerated shell bath freezers provide an easy way of pre-freezing many flasks at a time. Reliable motor-drive rollers rotate the flasks automatically to create an even layer. A flask lift device prevents fouling of lid and opening:

  • temperature to -75°C – decreasing manifold freeze drying time
  • rotates the flask on its axis, coating the interior surface of the flask – creating a larger surface area exposed to the low pressure of the freeze dryer, enhancing lyophilization rates; this reduces the freeze drying process to the shortest time possible when using flasks and a manifold system
  • accommodates a variety of flasks
  • single or dual bath
  • easy to install.

Pilot/ R&D Freeze Dryers

Genesis

Our most versatile freeze dryer for pilot, research or small-scale production applications. Its advanced product monitoring and process control make it ideal for research – especially in laboratories researching multiple products or formulations.

Specify Genesis with up to six bulk drying shelves (five vial processing shelves). Configure it to process a wide variety of vial sizes.

Genesis has a user-friendly, ergonomic layout – making it quicker and easier to use. Store up to 16 different multi-step freeze drying recipes.

Genesis has a 0.85m² shelf area and condenser capacity up to 35 litres. Options include:

  • stoppering
  • cleanroom configuration
  • isolation valve
  • water cooling
  • sample thief
  • installation and operator training
  • IQ and OQ options
  • control system options for 21CFR11 and cGMP compliance
  • PC software for data storage and handling.

Ultra

Similar to Genesis – highly flexible and with multiple configurations – but with greater capacity for small-scale production or to create later batches in scale-up research. Options include all those listed for Genesis.

In addition, the Ultra has a 2.13m² shelf area and condenser capacity up to 50 litres. Each shelf can accommodate 12 x 96 well plates. The total batch size is 180 plates when using 15 shelves. Ultra is used by pharmaceutical, biotech and diagnostics companies.

Lyostar

Reduce cycle development to just one or two runs instead of the typical six to eight runs!

Lyostar3 has a cutting-edge R&D system – SMART Freeze Drying Technology that enables fast and easy optimisation of cycles, ensuring smoother scaling up from laboratory to production.

Independent studies have confirmed that that Lyostar cuts the average cycle development by 78%.

Lyostar3 utilises ControLyo controlled nucleation technology – its rapid decrease in pressure causes each vial to nucleate at the same time; this is very important when considering batch-to-batch reproducibility.

Tunable Diode Laser Absorption Spectroscopy (TDLAS) enhances process performance understanding by using non-intrusive measures (such as water vapour presence, flow velocity and water mass flow.

VirTual

VirTual freeze dryers are designed for processes with high vapour loads – such as bulk processing or fast cycles.

The high-capacity 50 litre internal condenser is configured to add the enhancements of an external condenser while preventing any vapour impedance during bulk drying.  All chamber surfaces are manufactured from polished, easy-to-clean stainless steel. Multi-step, multi-recipe storage and optional external PC control provides the user with flexibility in cycle development, historical trending and repeatability.

Options enable compliance with modern industry manufacturing and laboratory standards including 21CFR11.

Production Freeze Dryers

BPS Crowthorne harnesses the knowledge of Biopharma Group’s more than 30 years’ experience in supplying high quality production freeze dryers with precision control tools to world-class pharmaceutical and biotech companies. They include the Ultra freeze dryers listed above in the Pilot Research Freeze Dryers section.

Our equipment specialists can help to specify the production lyo system that best suits your requirements. We work with leading manufacturers to install production freeze dryers with a wide range of specifications and configurations including:

  • CIP and SIP systems for advanced cleaning and sterilisation
  • loading systems, automatic loading and unloading (ALUS)
  • flap doors (pizza oven type doors).

All supplied production freeze dryers are compliant with 21 CFR Part 11 international standards and GMP (cGMP and GAMP5). Complete documentation is available for each device.

Our technical service team can help you with commissioning, operator training and installation qualification to ensure that your system meets your operational requirements and complies with regulatory standards.


Technical Servicing & Maintenance

All freeze dryers must be maintained and serviced regularly to ensure optimum performance and consistent results.

Biopharma Group provides a full range of technical services. Our experienced team maintains close links with suppliers – enabling us to support an installed base of more than 400 freeze dryers of all sizes and configurations.

We can also train your in-house service engineers to conduct day to day maintenance on your lyophilization equipment. Installation and operator training is available on all our systems and is provided as standard with most freeze dryers.

Qualification and validation packages are increasingly common even for smaller systems. We can tailor this service to your specific requirements. Packages can include supervised Factory Acceptance Tests and Site Acceptance Tests. We can provide protocols (or write them to your standards). Our expert team can also help you to prepare User Requirement Specifications (URS).


 

Get Expert Advice On Freeze Dryers

Specifying the best freeze dryer for your current and future operational needs requires expert technical advice. Some product features cannot be retrofitted.

Contact Biopharma Group’s freeze dryer specialists for advice on how to specify the right freeze dryer to improve consistency of results, reduce cycle times, increase efficiencies and cut costs.

 
 

Make Your Selection Below

 

Aseptic Processing Line & Fill-Finish Equipment Sterile Filling Systems External Vial Washers Sterilising Tunnels Rotary Vial Washers Capping Machines Fillers & Stoppering Trayloaders

Aseptic Processing Line & Fill-Finish Equipment Sterile Filling Systems External Vial Washers Sterilising Tunnels Rotary Vial Washers Capping Machines Fillers & Stoppering Trayloaders
 

Aseptic Processing Line And Fill-Finish Equipment

Choose from a wide range of equipment to create complete aseptic processing lines and fill-finish options for your freeze drying operations.

 

Rotary Vial Washers

Our user-friendly RW series rotary vial washers will reduce particulates by up to 1,000 times. Their innovative design improves operational efficiency and cuts costs:

  • spray manifold eliminates the risk of chipping vials
  • simple servo-driven operation – fewer moving parts, lower water usage and less maintenance
  • quick and easy to change between different sizes of glass and plastic vials
  • small footprint to suit virtually any manufacturing space
  • minimal operator intervention.

RW rotary vial washers are the smart alternative to labour-intensive batch-style vial washers. Benefits include:

  • 8 vial holders that hold up to 6 vials at the neck (RW-1150 has 16 vial holders)
  • transparent cover for visual verification of the washing process
  • dedicated media manifolds (one for water, one for air)
  • GMP design, all 304/316L stainless steel construction
  • intrinsically designed for 3-log endotoxin reduction
  • Allen-Bradley Micrologix 1100 PLC that works in conjunction with an Allen-Bradley PanelView Component C400 Touch Terminal HMI (RW-250) or Allen-Bradley PanelView 600+ operator interface (RW-500, RW-800)
  • no penetrating nozzles, no glass breakage, less particulate generation
  • internal surfaces are electro-polished
  • orbital welding is used whenever possible
  • piping system runs from high to low to prevent water stagnation
  • optional WFI-skid to supply the WFI at 80°C (no need for a WFI-loop)
  • complete validation documents package available (FRS, DDS, FAT/SAT, IQ/OQ)
  • self-draining after the end of the batch.

Choose from the following models:

  • RW-250 – for low speed, semi-automatic pharmaceutical and biotech applications. Minimal footprint, semi-automatic rotary vial washer for 2-100 ml vials. Up to 70 vials/minute output. Typical batch size is 1,000-8,000 vials.

RW-500 – automatic rotary vial washer for pharmaceutical and biotech applications. Up to 120 vials/minute. Typical batch size is 10,000-25,000 vials.

  • Rotary infeed table with automatic loading of the vials into the vial holders
  • Recycling of WFI, intermittent spraying and automatic lid lift mechanism
  • Main drive is servo-driven
  • Each vial format has an HMI-selected ‘recipe’ with specific settings for spray time and indexing time to help reduce water consumption
  • Water for injection (WFI) can be recycled, filtered and used a second time, further reducing water consumption
  • Silicone seals are used throughout the piping system.

The RW-500TL enables vial washing with automatic trayloading. Vial range 2-100 ml. Output up to 100 vials/minute. The outfeed of the washer and the trayloader can be placed under a vertical laminar airflow unit to ensure cleanliness. Features include: ‘no-tray present, washer does not start-up’ and ‘tray full, washer stops’.

RW-800 – medium-speed automatic rotary vial washer for 2-250 ml vials with output of up to 200 vials/minute. Typical batch size is 10,000-25,000 vials.

  • Vials are fed to the carriers by infeed drive belt
  • Vials leave the washer in single file
  • Rotary infeed table with automatic loading of the vials into the vial holders
  • Safety provisions prevent water spraying when the cover is not located over the washing chamber
  • Main drive is servo-driven
  • Each vial format has an HMI-selected ‘recipe’ with specific settings for spray time and indexing time to help reduce water consumption
  • Water for injection (WFI) can be recycled, filtered and used a second time, further reducing water consumption
  • Silicone seals are used throughout the piping system.

RW-1150 – high-speed automatic rotary vial washer. Up to 400 vials/minute for pharmaceutical and biotech applications. Typical batch size is 10,000-25,000 vials.

  • 16 vial holders that hold vials at the neck
  • Vials are fed to the carriers by infeed belt drive
  • Vials leave the washer in a single file
  • Rotary infeed table with automatic loading of the vials into the vial holders
  • Infeed vial flip table is ergonomically designed to avoid repetitive wrist motion, has a quicker plastic removal (2-3 times faster), and less chance of fallen vials
  • Safety provisions stop water spraying when the cover is not located over the washing chamber
  • 14 effective water/air stations
  • Combined exposure time is approximately 20 seconds based on 30 indices per minute
  • Recycling of WFI, intermittent spraying and automatic lid lift mechanism
  • Main drive is servo-driven
  • Four-level dual-password-protected menu guides the operator through the operations of the machine
  • Water for injection (WFI) can be recycled, filtered and used a second time, further reducing water consumption
  • Tank includes high- and low-level control mechanisms, automatically adding water on detection of low level
  • Internal immersion heating element helps maintain water temperature.

Sterilising Tunnels

‘Set-and-forget’ fully automatic sterilising tunnels for continuous aseptic processing of vials, syringes and ampoules.

The laminar airflow tunnels are highly effective thanks to the guaranteed thermic cycle, regardless of pressure fluctuations. In under 30 minutes, an untreated vial goes from vial washer to sterilising tunnel to cleanroom (fully sterilised – free of any microorganisms and pyrogens).

The tunnels continuously sterilise and depyrogenate pharmaceutical glass containers in a Class 100 environment at 320°C. This temperature gives a:

  • 1-log reduction in the bacterial endotoxin level in 9.5 seconds
  • 4-log reduction in 38 seconds
  • 6-log reduction in 57 seconds.

Vials travel from the vial washer via sanitary conveyor before an oscillating pusher gently moves them into the tunnel.

Silicon-controlled rectifier elements generate the heat; vials stay inside the sterilising chamber for approximately 6-10 minutes. Recirculated hot air is blown at a speed of approximately 0.7m/s over the vials (remaining within 2°C of the setpoint).

There are three chambers for pre-heating, sterilising and cooling. They are separated by gates with the height set automatically as part of the vial recipe. Each chamber has:

  • provision to DOP test the HEPA filters
  • a pipe below the filters to allow for particle counting.

SP i-Dositecno sterilising tunnels are fully compatible with vial handling solutions and trayloaders (including PennTech models). They can be integrated into new or existing installations.

Fillers And Stoppering 

Aseptic Fillers 

Choose from filler machine options that are ideal for containment and sterility. They are compatible with restricted access barriers (RABs) or isolator enclosures. Available for:

  • manual/semi-automatic debagging and delidding for pre-sterilised glass
  • cleanroom unscramblers for ophthalmic containers.

The fillers are compliant with 21 CFR Part 11 and are audit-trail capable.

LI, BI and SY aseptic fillers can handle up to 200 vials per minute. They are suitable for injectables, oral medicines, ophthalmics, syringes and cartridges.

LI linear fillers – stoppering/tip placement/pump inserting and crimping or closing machine for bottles and vials. Up to 12,000 u/h (units per hour). Able to work with stainless steel or ceramic rotary piston pumps or peristaltic pumps.

BI rotary fillers – rotary filling, stoppering/tip placement/pump inserting and crimping or closing machine for bottles and vials. Up to 6,000 u/h (units per hour).

SY syringe fillers – robotic filling machine with mechanical or vacuum plunger introduction for glass and plastic syringes, cartridges and vials in nest:

  • up to 6,000 u/h (units per hour) with two nozzles
  • 12,000 u/h (units per hour) with five nozzles
  • 24,000 u/h (units per hour) with ten nozzles.

The system is able to work with stainless steel or ceramic rotary piston pumps or peristaltic pumps (possible standard filling with mechanical plunger introduction or vacuum plunger introduction).

Automatic nest unloading and loading of tubes. The cleanroom-style robot is used to position syringes for filling and stoppering. Machines are also available for de-nesting, plunger insertion and labelling of syringes and cartridges.

All these units can be integrated with a vial washer, depyrogenation tunnel, freeze dryer (and freeze dryer loading systems), cappers, external vial washers and tray loaders to provide an integrated full-line solution.

Sterile Filling System

Precision-quality i-Dositecno sterile filling systems for vials and syringes cover a wide range of requirements from 0.1 ml to 500 ml (vials) and 0.1 ml to 20 ml (syringes).

Systems for injectables have been developed to fill vials and syringes covering a large range of products up to to 500ml in vials and up to 20ml in syringes.

For ophthalmic solutions, we offer options to handle bottle sizes up to 500ml for standard eye-droppers and screw capping styles, to systems such as the new Aptar filtered cap.

Systems range from peristaltic pumps to complex ceramic rotary pump with CIP/SIP system integration. Compliance includes CFR 21 Part 11, track and trace control and Inline Process Control (IPC).

Sterile Fillers And Cappers For Ophthalmic Liquids

The ophthalmic market has very stringent regulatory standards. The MI-O Series sterile filling & capping machine is for medium and low-speed processing, that can adhere and comply to these requirements. This allows for a complete sterile solution that can handle the special materials utilised for this market.

MI-O Series filling and capping machines are designed specifically to be used in laboratories for ophthalmic eye-dropper bottles. They can fill up to 6,000 b/h (bottles per hour). Specifications include:

  • intermittent rotary filler for doses from 1 ml to 500 ml.
  • formats up to 80 mm ø in simple configuration – maximum output 3,000 per hour
  • formats up to 26 mm ø in double configuration – maximum output 6,000 per hour
  • manufactured from 304 stainless steel to cGMP and FDA standards (elements in contact with product are 316L stainless steel)
  • up to four heads
  • can be sterilised by H2O2
  • nozzles have special rugosity for sterile products
  • no bottle, no fill
  • DQ documentation
  • bottles are fed by turntable or unscrambler
  • vials are filled by peristaltic pump, stainless steel rotary pump, ceramic rotary pump, CIP/SIP rotary pump.

Sterile Injectables (MI-I and BI-I Series)

The sterile injectables market is also very demanding. The equipment developed by SP i-Dositecno for this market offers a very high standard solution with processing speed capabilities of up to 9,000 u/h (units per hour). In this product range we can offer maximum benefits such as isolators for high containment requirements, oRAB’s and cRAB's, IPC control with check weighing across 100% of the process, CFR 21 part 11 compliance and smooth, accurate production.

The SY Series, MI-I Series and BI-I Series machines are able to work with dehydrogenating tunnels or pre-sterilized vials, and are suitable to be sterilised inline (with CIP/SIP equipment and H2O2) or by means of autoclave. Included is a package of Pharmaceutical cGMP and FDA compliant documentation.

SY Series – Filling machine for syringes, vials and cartridges up to 6,000 u/h (units per hour). Filling dose simplex 0.1 ml – 20 ml.

MI-I Series – designed specifically for sterile pharma filling; able to fill liquid and pharma powder with an output up to 6,000 b/h (bottles per hour)

BI-I Series – a table top machine designed for sterile filling of liquid and powders, that has an output of up to 2,000 b/h (bottles per hour).

Capping Machines

Cap up to 200 vials per minute with machines for aseptic injectable, oral, nasal spray and opthalmic applications.

Your vials will be protected: features include vertical force control during capping and torque control/strain gauge feedback for screw capping.

Our CRS-200 (continuous rotary motion) and LI-C (linear) capping machines suit virtually all manufacturing facilities. They are:

  • compatible with restricted access barriers (RABs) or isolator enclosures
  • compliant with 21 CFR Part 11
  • audit trail capable.

All the machines are manufactured from stainless steel with tempered glass doors and windows. The stainless steel hinges have built-in safety switches. Their sanitary, raised track conveyor makes cleaning easy. No stopper, no cap pick up. There is a reject station available.

LI-C and CRS-200

 
 

These machines are designed for low- to medium-speed pharmaceutical, biotech and animal health capping applications – 2-100 ml vials (up to 200 caps per minute):

  • six-head heavy-duty inline rotary capping machine
  • menu-driven operation (via Allen-Bradley PLC and PanelView Plus 1000)
  • PLC-assisted changeover
  • GMP design
  • sanitary, raised track conveyor for easy cleaning
  • no stopper, no cap pick up
  • reject station available
  • electrical cabinet located within the machine’s frame
  • 13, 20 and 32 mm flip-off caps
  • comprehensive machine documentation with exploded 3D assembly drawings
  • complete validation documents package available (FRS, DDS, FAT/SAT, IQ/OQ)
  • dimensions 185 × 97.8 x 197 cm, vial running surface 85-95 cm.

External Vial Washers

EVW-Series machines are the only external vial washers to fully encapsulate caps with a watertight seal:

  • stopping the cleaning agent from entering the cap area
  • preventing any future bacterial contamination

Operation is menu-driven via the human machine interface (HMI). PLC-controlled servo motors automatically set the output rate, vial height and water/air flow per vial size.

Changing to a different cap or vial format is tool-less. It takes less than 15 minutes.

Equipment documentation and validation protocols are among the best in the industry. Every machine comes with:

  • ‘As-Built’ 3D exploded assembly drawings (each with a list of materials)
  • material and welding certificates with corresponding isometric drawings
  • complete operator and maintenance instructions, electrical drawing package and PLC/HMI programs.

All EVW-Series machines available from BPS Crowthorne offer the following technical benefits:

  • Each machine can be used as a stand-alone unit with an infeed and outfeed turntable – or integrated into a filling line
  • Equipped as standard with an Allen Bradley CompactLogix PLC and an Allen Bradley PanelView Plus 600 HMI (Siemens is available as an option on the EVW-60)
  • No alignment of spray nozzles
  • No format parts are needed for 13 and 20mm caps
  • Piping system and electrical cabinet are installed inside the frame of the machine – for a small footprint and a clean installation
  • Rinsing with low pressure water cleans the vials from the neck down (while they rotate)
  • Vials leave the machine dry (drying is by compressed facility air or by an on-board air blower in the machine’s base)
  • Stainless steel, heavy duty construction with tempered glass windows and doors.

Choose from the following machines…

EVW-60 H4

  • 2-100 ml vials (up to 100/minute)
  • Optional negative pressure can be obtained in the enclosure by installing an exhaust with HEPA-filter on the unit’s top
  • Dimensions – 51.8 x 127 x 127.4 cm

EVW-100 H4

  • 2-500 ml vials (up to 400/minute)
  • Five-minute changeover (no tools needed, only change part is the vial timing screw)
  • Password-protected machine controls
  • Accident prevention hood or under pressurised hood with gloves ports is available
  • Dimensions – 209.5 × 84.5 x 198 cm (vial running surface is 85-95 cm)

High Output External Vial Washer

  • 2-500 ml vials (up to 500/minute)
  • Five-minute changeover (no tools needed, only change part is the vial timing screw)
  • Password-protected machine controls
  • Accident prevention hood or under pressurised hood with gloves ports is available
  • Dimensions – 360 × 84.5 x 198 cm
 
 

Trayloaders 

Choose TL trayloaders for medium- to high-output aseptic and non-aseptic applications. They can handle plastic and glass vials up to 500 ml (up to 400 vials per minute).

TL trayloaders’ smart work area layout and design means:

  • simple operation
  • quick and easy changeover between vial sizes for minimal downtime (tool-free, less than two minutes)
  • no interruption of vertical airflow
  • ease of cleaning.

Stepper motor speed and actuator movement is specific to each vial type and size – thanks to PLC control. TL trayloaders also offer the following benefits:

  • Controlled by Programmable Logic Controller (PLC), will handle plastic and glass vials
  • Can handle metal, cardboard or plastic (corrugated or rigid) trays up to 610 mm (24″) wide (open end) and up to 610 mm (24″) deep
  • No format/change parts required
  • Menu-driven, PLC-assisted changeover
  • Automatic nesting
  • Optional automatic containment ring lowering system for freeze drying applications
  • Optional camera inspection to ensure same cap colour/format and vial configuration
  • Consistency in trayloading – always the same number of vials per tray
  • Non-stop loading, even when replacing a full tray.

TL-100 Single Trayloader

  • Dimensions: 208 x 112 x 95 cm (vial running surface 85-95 cm)
  • Vials: 2-500 ml (up to 200 vials per minute, depending on vial diameter and tray size)
  • Changeover is tool-less and can be achieved in 2 minutes

TL-200 Dual Trayloader

  • Dimensions: 297.5 x 112 x 95 cm (vial running surface 85-95 cm)
  • Vials: 2-500 ml (up to 400 vials per minute, depending on vial diameter and tray size)
  • Changeover is tool-less and can be achieved in 2 minutes

HSTL-200 Dual Trayloader

  • Dimensions: 297.5 x 112 x 95 cm (vial running surface 85-95 cm)
  • Vials: 2-500 ml (up to 500 vials per minute, depending on vial diameter and tray size)
  • Changeover is tool-less and can be achieved in 2 minutes

 

Get Expert Advice On Freeze Dryers And Aseptic Processing Lines

Choosing the best freeze dryers, aseptic processing line and fill-finish equipment for your current and future operations requires expert technical advice. Some product features cannot be retrofitted.

Contact BPS Crowthorne’s product specialists for advice on how to specify the right equipment to improve consistency of results, reduce cycle times, increase efficiencies and cut costs.